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ACETYL CARNITINE

CAS 14992-62-2
90

Safety score · 0–100

Excellent

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A naturally occurring amino acid derivative that acts as a humectant and skin conditioning agent, promoting cellular energy and protecting against oxidative stress.

The acetyl ester of L-carnitine (INCI: Acetyl Carnitine), a conditionally essential quaternary ammonium zwitterion involved in mitochondrial fatty acid oxidation. Widely used in both topical cosmetics and nutritional supplements. The acetyl group enhances skin penetration compared to carnitine itself. Not subject to EU Regulation 1223/2009 Annex restrictions. Reviewed by the SCCS with no safety concerns at current cosmetic use concentrations.

Skin benefits

  • Humectant - attracts moisture to skin
  • Cellular energy support via mitochondrial function
  • Antioxidant protection
  • May support collagen production

Known concerns

  • Minimal concerns at cosmetic use levels
  • Generally recognized as safe in supplements and topical formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.