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ACETYLPHYTOSPHINGOSINE

CAS -
90

Safety score · 0–100

Excellent

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An acetylated derivative of phytosphingosine, functioning as a skin-identical lipid and ceramide analog in cosmetic formulations.

Acetylphytosphingosine is an acetylated sphingolipid derived from phytosphingosine, a type of ceramide precursor naturally found in the skin's stratum corneum. As a skin-identical ingredient, it integrates well into the skin barrier and supports ceramide synthesis pathways. It has no EU cosmetic prohibition entries and is not classified under major hazard frameworks, consistent with its high PubChem safety score of 90 indicating an excellent safety profile in topical applications.

Skin benefits

  • skin-identical lipid ingredient
  • supports ceramide synthesis
  • strengthens skin barrier function
  • excellent tolerability

Known concerns

  • no major safety concerns identified
  • no EU restrictions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.