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chlorphentermine

CAS 461-78-9
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Chlorphentermine is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Chlorphentermine is a sympathomimetic amine with anorexiant (appetite-suppressing) properties, structurally related to amphetamine. It was used as a pharmaceutical agent for weight loss but was withdrawn from markets globally due to association with pulmonary arterial hypertension. It has no function, approval, or historical use in cosmetic formulations. The compound is not listed in EU cosmetics regulation because it has never been a cosmetic ingredient. Its presence in any ingredient database for cosmetics represents a misclassification or cross-category confusion with pharmaceutical substances.

Known concerns

  • Withdrawn pharmaceutical substance
  • Associated with pulmonary arterial hypertension
  • No cosmetic use or approval
  • Not a cosmetic ingredient

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.