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Cholecalciferol [USAN:BAN:JAN]

CAS 67-97-0
93

Safety score · 0–100

Excellent

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Cholecalciferol [usan:ban:jan] is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Cholecalciferol (Vitamin D3) is a fat-soluble vitamin regulated under EU Cosmetics Regulation as a recognised cosmetic ingredient. It is listed on CosIng with skin-conditioning function. While essential for skin health, systemic absorption can occur and the SCCS has noted concerns regarding vitamin D levels from cosmetic use. In the EU, vitamin D is not restricted by Annex II/III but is monitored for safe use concentration.

Skin benefits

  • Supports skin barrier function
  • May aid in skin cell regulation
  • Conditioning agent for skin

Known concerns

  • Systemic absorption may affect vitamin D levels
  • High doses can cause hypervitaminosis D with prolonged use
  • Not permitted in cosmetic products intended for lips or mouth area in some member states

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.