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CIVETONE

CAS 542-46-1
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A natural macrocyclic ketone fragrance compound derived from civet secretion, used to impart warm, musky notes in perfumes. While not acutely toxic, it is classified as a fragrance allergen requiring declaration in EU cosmetics.

Civetone (9-cis-cycloheptadecen-1-one) is a macrocyclic ketone that occurs naturally in civet musk. It is listed in EU CosIng but not specifically restricted under Annex III, though fragrance allergens in general require declaration under Regulation (EC) No 1223/2009 when present above 0.01% in leave-on products. The substance has limited aquatic toxicity data but is not considered a high-risk cosmetic ingredient.

Known concerns

  • fragrance allergen — requires EU label declaration
  • limited aquatic toxicity data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.