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clonazoline

CAS 17692-28-3
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Clonazoline is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Clonazoline is an imidazoline derivative with alpha-2 adrenergic agonist and vasoconstrictive properties, historically used as a nasal decongestant. It has no entry in the EU CosIng database as a permitted cosmetic ingredient and is considered a pharmacologically active substance prohibited in cosmetic formulations under EU Regulation (EC) No 1223/2009. No SCCS safety assessment exists for this ingredient in cosmetic contexts.

Known concerns

  • Pharmacologically active imidazoline — not permitted in cosmetics
  • No EU CosIng entry
  • Potential systemic absorption and sympathomimetic side effects

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.