Skip to content

Other

diethylthiambutene

CAS 86-14-6
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Diethylthiambutene is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Diethylthiambutene is a structural analogue of dimethylthiambutene, sharing the same 3,3-diethyl-1-methyl-4-phenylpiperidine-4-like thiambutene backbone. It is a mu-opioid agonist with analgesic potency comparable to morphine. No safety dossier exists for cosmetic or topical use. Under EU Regulation (EC) No 1223/2009 Annex II (substances prohibited in cosmetic products), opioid pharmacophores without cosmetic benefit are explicitly prohibited.

Known concerns

  • Potent opioid agonist — severe opioid toxicity risk
  • Prohibited in EU cosmetics Annex II
  • No cosmetic safety data
  • High dependence liability

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

8
1,4-Dichlorobenzene (p-Dichlorobenzene)
Other
 8
1-Chloro-4-nitrobenzene
Other
 8
1-Methyl-3-nitro-1-nitrosoguanidine
Other
 8
2,2,2-Trichloroethane-1,1-diol
Other
 8
2,3-EPOXYPROPYLTRIMONIIUM CHLORIDE
Other
 8
2-Methylheptylamine and its salts
Other
 8
3-Oxoandrost-4-ene-17-ß-carboxylic acid
Other
 8
4-o-Tolylazo-o-toluidine
Other

Check your shelf

Find diethylthiambutene in your products.

Scan any cosmetic product with LuxSense to see if it contains diethylthiambutene and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.