Other
dimethylthiambutene
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Dimethylthiambutene is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
Dimethylthiambutene is a synthetic opioid of the thiambutene series, structurally distinct from morphine but sharing potent mu-opioid agonist activity. Like the related compounds diethylthiambutene and ethylmethylthiambutene, it has no history of cosmetic use and no safety data for topical exposure. Under EU Regulation (EC) No 1223/2009 Annex II, it would be classified as a prohibited pharmacological substance. Its inclusion in any ingredient database for cosmetics is an error or indicator of a contaminated raw material.
Known concerns
- Potent opioid agonist — risk of respiratory depression
- Prohibited in EU cosmetics Annex II
- No cosmetic safety assessment exists
- High abuse potential
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.