Skip to content

Other

dimethylthiambutene

CAS 524-84-5
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Dimethylthiambutene is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Dimethylthiambutene is a synthetic opioid of the thiambutene series, structurally distinct from morphine but sharing potent mu-opioid agonist activity. Like the related compounds diethylthiambutene and ethylmethylthiambutene, it has no history of cosmetic use and no safety data for topical exposure. Under EU Regulation (EC) No 1223/2009 Annex II, it would be classified as a prohibited pharmacological substance. Its inclusion in any ingredient database for cosmetics is an error or indicator of a contaminated raw material.

Known concerns

  • Potent opioid agonist — risk of respiratory depression
  • Prohibited in EU cosmetics Annex II
  • No cosmetic safety assessment exists
  • High abuse potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

8
1-Methyl-3-nitro-1-nitrosoguanidine
Other
 8
2,2,2-Trichloroethane-1,1-diol
Other
 8
2,3-EPOXYPROPYLTRIMONIIUM CHLORIDE
Other
 8
2-Methylheptylamine and its salts
Other
 8
3-Oxoandrost-4-ene-17-ß-carboxylic acid
Other
 8
4-o-Tolylazo-o-toluidine
Other
 8
6-Nitro-o-toluidine
Other
 8
8,8'-diapo-.psi.,.psi.-Carotenedioic acid
Other

Check your shelf

Find dimethylthiambutene in your products.

Scan any cosmetic product with LuxSense to see if it contains dimethylthiambutene and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.