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dimethylthiambutene

CAS 524-84-5
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Dimethylthiambutene is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Dimethylthiambutene is a synthetic opioid of the thiambutene series, structurally distinct from morphine but sharing potent mu-opioid agonist activity. Like the related compounds diethylthiambutene and ethylmethylthiambutene, it has no history of cosmetic use and no safety data for topical exposure. Under EU Regulation (EC) No 1223/2009 Annex II, it would be classified as a prohibited pharmacological substance. Its inclusion in any ingredient database for cosmetics is an error or indicator of a contaminated raw material.

Known concerns

  • Potent opioid agonist — risk of respiratory depression
  • Prohibited in EU cosmetics Annex II
  • No cosmetic safety assessment exists
  • High abuse potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.