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Skin Conditioning

DIPEPTIDE-80 HCL

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic 2-amino-acid peptide supplied as the HCl salt. Used as a skin-conditioning agent at trace levels; data is limited.

Dipeptide-80 HCl is a synthetic dipeptide (2 amino acids) supplied as the hydrochloride salt for cosmetic skin-conditioning use, typically at parts-per-million levels. Dipeptides are very small molecules with negligible intact skin penetration; the HCl form is common when one of the residues bears a basic side chain. There is no CIR or SCCS opinion specific to this peptide and no published GHS classification. Irritation potential at use levels is low. The HCl salt may need pH balancing in the finished formulation. Independent efficacy data is sparse; signal-style claims are supplier-generated.

Function

SKIN PROTECTING

Skin benefits

  • Skin conditioning
  • Amino-acid based
  • Low irritation potential

Known concerns

  • No regulatory monograph
  • Sparse independent data
  • Salt form needs pH consideration

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.