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Epinephrine (INN)

CAS 51-43-4
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Epinephrine (inn) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Epinephrine (also called adrenaline) is a catecholamine hormone and neurotransmitter with potent cardiovascular effects, causing vasoconstriction, increased heart rate, and bronchodilation. In the EU, it is classified as a prescription-only medicine. The SCCS has not assessed epinephrine for cosmetic safety, and its use in cosmetics is considered inappropriate given its pharmacological potency and potential for serious systemic adverse effects even from topical application.

Skin benefits

  • Vasoconstrictive properties may reduce skin redness temporarily

Known concerns

  • Prescription-only pharmaceutical in the EU
  • Potent cardiovascular effects (vasoconstriction, tachycardia)
  • No SCCS cosmetic safety assessment
  • Risk of systemic adverse effects from topical application
  • Not authorised in any EU cosmetic annex

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.