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ETHYL CROTONATE

CAS 10544-63-5
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Ethyl Crotonate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Ethyl crotonate (CAS 10544-63-5) is the ethyl ester of crotonic acid, featuring an alpha,beta-unsaturated carbonyl system that makes it chemically reactive compared to saturated esters. The electrophilic nature of the double bond raises concerns for skin and respiratory sensitization. While not specifically listed in EU Annex II or III under Regulation 1223/2009, the presence of an α,β-unsaturated ester moiety is a structural alert for potential toxicity. The compound is primarily used in industrial coatings and as a chemical intermediate; its use in cosmetics is limited and should be approached with caution, particularly in leave-on formulations. The safety score reflects the structural concern level.

Skin benefits

  • Fragrance material with unique sharp fruity character
  • Industrial applications

Known concerns

  • α,β-unsaturated carbonyl structural alert
  • Potential skin sensitizer
  • Chemical reactivity higher than saturated analogues
  • Limited cosmetic-specific safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.