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GEROTINE

CAS 71-44-3
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A historic hair dye intermediate restricted under EU Annex II/411 due to toxicity concerns, making it prohibited for use in cosmetic products throughout the EU.

Gerotine corresponds to 2,4-diaminoanisole (CAS 71-44-3), an aromatic amine formerly used in hair dye formulations. It is listed in EU Cosmetics Regulation Annex II (list of substances prohibited in cosmetic products) under reference II/411. Annex II is the most restrictive list—substances there are outright banned from cosmetic products in the EU due to concerns around toxicity, mutagenicity, or carcinogenic potential. The compound's restriction predates current REACH assessment requirements.

Known concerns

  • EU Annex II banned (II/411)
  • Prohibited in all cosmetic products in the EU

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.