Skip to content

Other

Guanethidine (INN) and its salts

CAS 55-65-2
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Guanethidine (inn) And Its Salts is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Guanethidine is a licensed antihypertensive drug that acts as a sympathetic nerve blocker. As a pharmaceutical with no cosmetic application, it is not permitted in cosmetic products under EU Regulation 1223/2009. Side effects at therapeutic doses include hypotension, dizziness, and bradycardia, making its presence in cosmetics entirely inappropriate.

Known concerns

  • Cardiovascular effects (severe hypotension, bradycardia)
  • Dizziness and syncope risk
  • Prohibited pharmaceutical substance in cosmetics
  • No cosmetic application whatsoever

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

18
1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride
Other
 18
2,2'-METHYLENEBIS-4-AMINOPHENOL HCL
Other
 18
2-HYDROXYETHYL ACRYLATE
Other
 18
3-Ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine
Other
 18
ALUMINUM ISOPROPOXIDE
Other
 18
AMMONIUM TRICHLOROACETATE
Other
 18
BASIC GREEN 4
Other
 18
CYCLOPROPYLMETHYLBIMATOPROST
Other

Check your shelf

Find Guanethidine (INN) and its salts in your products.

Scan any cosmetic product with LuxSense to see if it contains Guanethidine (INN) and its salts and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.