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HC BLUE NO. 12

CAS 132885-85-9 / 104516-93-0
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A hair dye intermediate listed in EU Annex III (entry III/225) with permitted use conditions, primarily used in oxidative hair dye formulations at controlled concentrations.

HC Blue No. 12 is an aromatic heterocyclic amine-type hair dye intermediate listed in EU CosIng Annex III under entry III/225, which sets specific conditions and concentration limits for its use in cosmetic products. It is restricted to oxidative (permanent) hair dye formulations only and may not be used in products that can be applied to the oral mucosa. The restriction aims to limit exposure given potential sensitization concerns typical of hair dye intermediates.

Known concerns

  • EU Annex III restricted hair dye intermediate (III/225)
  • Potential skin sensitization from aromatic amine exposure
  • Restricted to oxidative hair dye use only

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Same plant / compound family

35
HC BLUE NO. 10
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 35
HC BLUE NO. 11
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HC BLUE NO. 13
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HC BLUE NO. 14
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HC BLUE NO. 15
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 42
HC BLUE NO. 16
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.