HC BLUE NO. 15

Other

40

Caution

CAS Number: 74578-10-2

About HC BLUE NO. 15

A blue hair dye ingredient — restricted in the EU due to safety concerns. The SCCS couldn't confirm it's safe even at its maximum allowed concentration of 0.2%.

Detailed Analysis

HC Blue No. 15 (CAS 74578-10-2) is a synthetic hair dye used in oxidative and semi-permanent formulations. The SCCS (2012) concluded it 'cannot be considered safe' for use at 0.2% on-head concentration due to a low margin of safety, pending better dermal absorption data. It is not genotoxic (confirmed by in vivo micronucleus test). The 90-day NOAEL is 4 mg/kg/day. Low dermal penetration observed but worst-case calculations raised concerns. EWG lists it as unacceptable for verified products. PubChem CID: 173294.

Known Concerns

  • SCCS could not confirm safety at max use level
  • EU restricted — max 0.2% in oxidative hair dyes
  • Potential skin sensitizer (insufficient data to rule out)
  • Irritating to mucous membranes undiluted
  • EWG classifies as unacceptable

Safety Score

40

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.