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Skin Conditioning

HEPTAPEPTIDE-37

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic seven-amino-acid peptide used in skin conditioning formulas. Low-risk by peptide-class behavior; specific evidence is sparse.

Heptapeptide-37 is a defined-sequence synthetic peptide of seven amino acids, marketed as a skin-conditioning active. It is typically used at very low concentrations in serums and treatment products. Like other short cosmetic peptides, it has a low intrinsic toxicity profile — the molecule is too large to cross skin readily, breaks down enzymatically into amino acids, and rarely sensitizes. No CIR or SCCS opinion has been published. Public efficacy literature is essentially limited to supplier-provided in vitro and small consumer-panel studies; independent replication is lacking.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Low irritation potential
  • Biodegrades to amino acids

Known concerns

  • Limited independent data
  • Supplier-driven efficacy claims
  • No formal regulatory dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.