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Skin Conditioning

HEXAPEPTIDE-58

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic six-amino-acid peptide used in skin-conditioning formulas. Low-risk by class; specific evidence is thin.

Hexapeptide-58 is a defined-sequence synthetic six-amino-acid peptide used as a skin-conditioning agent. Hexapeptides have a generally favorable safety profile in cosmetic use — too large to deeply penetrate, broken down to amino acids by skin proteases, low sensitization risk. There is no specific CIR or SCCS opinion. Independent peer-reviewed efficacy data is essentially absent; claims rely on supplier in vitro work.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Low irritation
  • Defined synthetic sequence

Known concerns

  • Limited independent data
  • No regulatory review
  • Supplier-driven claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.