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Sensory Actives

HYDROXYMETHOXYBENZYL PELARGONAMIDE

CAS 2444-46-4
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic capsaicin-like amide used to create a warming sensation in slimming and massage cosmetics. Effective but commonly classified as a skin irritant and potential sensitiser, so use is limited to small areas.

Skin benefits

  • Capsaicin analog used as a warming or slimming actives marker
  • May stimulate local microcirculation
  • Synthetic alternative to natural capsaicin with milder profile

Known concerns

  • PubChem GHS classification flags H315 skin irritation and H317 sensitisation for related nonivamide
  • Can cause burning, redness, and stinging on application
  • Risk of allergic contact dermatitis with repeated exposure
  • Not suitable for sensitive skin, eye area, or broken skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.