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Fragrance

ISOAMYL BUTYRATE

CAS 106-27-4
75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A fruity ester (pear/apricot note) widely used as fragrance and food flavor. Long safety record at cosmetic-level use.

Isoamyl butyrate (3-methylbutyl butanoate, CAS 106-27-4) is a fruity ester with pear, apricot, and tropical notes. It is one of the classic perfumery fruit-esters and is also approved as a food flavoring (FEMA GRAS, EU flavoring register). In cosmetics it is used as a fragrance ingredient. IFRA standards apply. It is not on the EU Annex III declarable-allergen list. Food-grade approvals and long use support a good safety baseline; at typical fragrance-use levels skin tolerability is good. In concentrated form it is a flammable liquid and a mild eye irritant, but those concerns are for bulk handling rather than finished products.

Skin benefits

  • Fruity, pear-apricot fragrance ester
  • Widely used in perfume and flavor
  • Food-grade approvals support cosmetic use

Known concerns

  • May sensitize fragrance-reactive users
  • IFRA guidance applies
  • Flammable liquid — bulk handling only

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.