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isomethadone

CAS 466-40-0
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Isomethadone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Isomethadone is a synthetic opioid related to methadone, classified as a narcotic substance under the 1961 UN Single Convention on Psychotropic Substances. Under EU Regulation (EC) No 1223/2009 (Cosmetics Regulation), Annex II lists substances prohibited in cosmetic products, which includes narcotic drugs. The ingredient has no established safe use in cosmetics and would be considered non-compliant in any EU-market cosmetic product.

Known concerns

  • Narcotic substance — prohibited in cosmetic products (EU Annex II)
  • No safety assessment available for cosmetic exposure
  • Controlled substance with abuse potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.