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ISOSTEARETH-50

CAS 52292-17-8
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Isosteareth-50 is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Isosteareth-50 (CAS 52292-17-8) is the polyethylene glycol ether of isostearyl alcohol (a branched C18 alcohol) with an average of 50 ethylene oxide units, making it a hydrophilic nonionic surfactant with strong water-binding capacity. The branched isostearyl chain provides superior emolliency and skin-feel compared to linear chain analogues, while the high degree of ethoxylation (50 units) makes it water-soluble and mild. EU cosmetic regulations permit ethoxylated fatty alcohols with appropriate purity specifications. The branched structure reduces crystallization and improves formulation aesthetics. Typical use in rinse-off and leave-on products is safe; the 50-EO unit count suggests low residual ethylene oxide concern relative to shorter ethoxylates.

Skin benefits

  • Strong water-binding humectant properties
  • Emollient and skin-softening effects from isostearyl chain
  • Nonionic surfactant with mild cleansing action

Known concerns

  • Ethylene oxide purity controls required per SCCS guidance
  • High HLB value may cause some defatting of skin with excessive use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.