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Skin Conditioning

LACTUCA SCARIOLA SATIVA LEAF JUICE

CAS 84776-66-9 / 90046-10-9
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Juice of cultivated/wild lettuce — a gentle, hydrating leaf juice. The bitter sap of the wild form contains lactones, so processed cosmetic grade is preferred.

Lactuca scariola sativa (wild/prickly lettuce as transitioned to the cultivated L. sativa group) leaf juice is used as a skin-conditioning and hydrating botanical. It is largely water, with small amounts of flavonoids (quercetin glycosides), vitamin C, and mineral salts. The latex-like sap of wild Lactuca species contains bitter sesquiterpene lactones (lactucin, lactucopicrin) that can cause contact sensitization in Asteraceae-sensitive users; cosmetic-grade juice is drawn from cultivated leaves and is essentially free of the bitter latex. CosIng lists it for skin conditioning. No CIR monograph. Overall safety at typical use levels is good; preservation is the usual formulation concern.

Skin benefits

  • Hydrating water-rich botanical
  • Mild flavonoid and vitamin content
  • Gentle cooling/refreshing feel

Known concerns

  • Wild lettuce (L. scariola) sap contains bitter sesquiterpene lactones
  • Possible contact sensitization in Asteraceae-sensitive users
  • Preservation required

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.