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LAPACHONE

CAS 4707-32-8
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Beta-lapachone, an ortho-naphthoquinone from Tabebuia bark. A pharmacologically active compound studied as an anticancer drug, not an established cosmetic ingredient. Class concerns: ROS generation and skin sensitisation.

Skin benefits

  • No established cosmetic benefit

Known concerns

  • Pharmacologically active drug candidate
  • Naphthoquinone class skin sensitisation
  • ROS-generating bioactivation
  • No CIR/SCCS review
  • Off-label cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.