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Antioxidant

LARREA DIVARICATA LEAF EXTRACT

CAS 91722-67-7 Updated
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Chaparral leaf extract — desert shrub rich in NDGA antioxidant. Oral use is linked to liver injury and FDA/Health Canada warnings; topical use warrants caution.

Function

SKIN CONDITIONING

Skin benefits

  • NDGA — potent antioxidant polyphenol
  • Skin conditioning
  • Antimicrobial activity

Known concerns

  • Chaparral linked to severe hepatotoxicity (oral) — FDA and Health Canada warnings
  • NDGA removed from FDA GRAS list
  • Allergic / immunological skin reactions reported
  • Long-term safety concerns even topically

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.