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Antioxidant

LARREA DIVARICATA EXTRACT

CAS 91722-67-7 Updated
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Creosote bush (chaparral) extract — rich in NDGA. Despite antioxidant potency, the species is FDA/Health Canada-flagged for severe hepatotoxicity and FDA pulled NDGA from GRAS; best avoided.

Function

ANTIOXIDANTFRAGRANCE

Skin benefits

  • Strong NDGA antioxidant activity
  • Traditional skin-soothing use

Known concerns

  • Chaparral / NDGA linked to severe hepatotoxicity (FDA, Health Canada, NIH LiverTox)
  • FDA removed NDGA from GRAS list
  • Idiosyncratic acute liver failure cases reported
  • Sensitisation risk on broken skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.