Antioxidant
LARREA MEXICANA EXTRACT
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Mexican chaparral (Larrea mexicana) extract — like its sister species L. divaricata, dominated by NDGA. Hepatotoxicity warnings and FDA NDGA-delisting make this a high-caution ingredient.
Function
Skin benefits
- Strong NDGA antioxidant activity
- Traditional skin-soothing use
Known concerns
- Chaparral / NDGA linked to severe hepatotoxicity (FDA, Health Canada, NIH LiverTox)
- FDA removed NDGA from GRAS list
- Idiosyncratic acute liver failure cases reported
- Sensitisation risk on broken skin
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related antioxidants
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.