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levomethorphan

CAS 125-70-2
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Levomethorphan is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Levomethorphan is the l-isomer of methorphan, used medically as a cough suppressant with opioid-like activity. It is not listed in EU cosmetic regulation annexes but is pharmacologically active in a manner similar to other opioid derivatives prohibited in cosmetics. EU regulatory guidance would treat this as a prohibited pharmacological substance under the general provision of Annex II.

Known concerns

  • Opioid-like CNS effects
  • Abuse potential
  • Not approved for cosmetic use in EU
  • Possible respiratory effects at systemic exposure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.