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methestrol

CAS 130-73-4
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Methestrol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Methestrol (also known as methestrole or 4,4'-(1,2-diethyl-2-methylethylenedioxy)dianiline) is a synthetic non-steroidal estrogen. The EU Cosmetics Regulation prohibits substances with endocrine-disrupting activity in cosmetic products. As an estrogenic compound, methestrol can interfere with hormonal function, and its use in cosmetics is banned. There is no legitimate cosmetic application for this pharmaceutical-class estrogenic substance.

Known concerns

  • Endocrine disrupting substance (estrogenic activity)
  • Prohibited in EU cosmetic products
  • Potential reproductive and developmental toxicity
  • Pharmaceutical drug substance with no cosmetic justification

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.