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MICONAZOLE NITRATE

CAS 22832-87-7
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A widely used topical antifungal agent approved in some jurisdictions for cosmetic applications such as anti-dandruff products, though EU CosIng listing and permitted concentrations should be verified.

Miconazole nitrate is the nitrate salt of the imidazole antifungal miconazole, used topically for candidiasis and dermatophyte infections. It is generally well tolerated when applied topically, though it can cause local skin irritation. Some regulatory bodies have approved it in anti-dandruff cosmetic formulations at low concentrations (up to 0.5%). In the EU, azole antifungals require verification of current CosIng status before formulation use, as some may be restricted or require additional safety data under the cosmetics regulation.

Skin benefits

  • Broad-spectrum topical antifungal activity
  • Used in anti-dandruff hair care formulations
  • Effective against Malassezia yeast associated with dandruff and seborrheic dermatitis

Known concerns

  • Local skin irritation possible in susceptible individuals
  • EU CosIng status should be verified for specific product type and concentration
  • Topical antifungal use may affect skin microbiome

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.