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Formaldehyde-releasing preservative

N,N''-Methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]urea]

CAS 39236-46-9
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A formaldehyde-releasing preservative in the imidazolidinyl urea family. Effective against microbes in water-based products but a recognized contact allergen, with growing avoidance in sensitive-skin formulas.

Skin benefits

  • Effective broad-spectrum preservative (imidazolidinyl urea family)
  • Helps prevent microbial spoilage of water-based cosmetics
  • Active across a wide pH range

Known concerns

  • Formaldehyde-releasing preservative
  • Established contact allergen, especially on facial skin
  • Avoided by clean-beauty and sensitive-skin formulators
  • Regulatory pressure in EU has led to declining acceptable concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related formaldehyde-releasing preservatives

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.