N-(Trichloromethylthio)phthalimide (Folpet - ISO)

Other

18

Avoid

CAS Number: 133-07-3

About N-(Trichloromethylthio)phthalimide (Folpet - ISO)

N-(Trichloromethylthio)phthalimide (Folpet - ISO) is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Detailed Analysis

Folpet (ISO) is a phthalimide-derived fungicide used in agriculture since the 1950s. Its hazard profile encompasses multiple serious concerns: H317 indicates skin sensitisation potential, H351 classifies it as a suspected carcinogen, H361 indicates reproductive toxicity, H372 indicates specific target organ toxicity with repeated exposure, and H330 indicates acute inhalation toxicity. Its trichloromethylthio group can dissociate to yield phthalimide and carbon disulfide. The compound is authorised as a pesticide but has no place in cosmetic formulations; the EU CosIng database does not list it as an authorised cosmetic ingredient.

Known Concerns

  • H317: May cause allergic skin reaction
  • H319: Causes serious eye irritation
  • H330: Fatal if inhaled
  • H332: Harmful if inhaled
  • H351: Suspected of causing cancer
  • H361: Suspected of damaging the unborn child
  • H372: Causes damage to organs through prolonged or repeated exposure
  • H400/H410: Very toxic to aquatic life / with long-lasting effects
  • No EU cosmetic authorisation — agricultural fungicide

Safety Score

18

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.