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NICKEL ACETYLMETHIONATE

CAS -
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A nickel salt of N-acetylmethionine. Nickel is the world's leading contact allergen and broadly restricted in skin-contact products — not an acceptable cosmetic ingredient.

Nickel acetylmethionate is a nickel salt of the amino acid N-acetylmethionine. Nickel is the most frequent cause of allergic contact dermatitis worldwide, affecting roughly 10-20% of women and 1-3% of men in patch-test populations. EU REACH Annex XVII entry 27 restricts nickel release from articles intended for direct and prolonged skin contact to 0.5 µg/cm²/week, and the EU Cosmetics Regulation generally excludes deliberate addition of nickel salts. Certain nickel compounds (sulfides, oxides) are IARC Group 1 carcinogens. There is no acceptable cosmetic use case; trace contamination in mineral ingredients is a separate quality-control issue.

Function

NOT REPORTED

Skin benefits

  • None

Known concerns

  • Leading global contact allergen
  • EU restricts nickel in skin-contact products
  • Certain nickel compounds are IARC Group 1
  • No acceptable cosmetic function

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.