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Skin Conditioning

NICOTINOYL DIPEPTIDE-24

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A two-amino-acid synthetic peptide N-conjugated to niacin — for skin conditioning. Generally well tolerated; mild flushing possible in sensitive users.

Nicotinoyl Dipeptide-24 is a synthetic dipeptide whose N-terminus is acylated with a nicotinoyl (niacin-derived) group. The intent is to combine peptide carrier behavior with niacin-related skin-conditioning effects. Niacin derivatives in cosmetics are widely used and generally well tolerated, though they can produce transient warmth or flushing in sensitive individuals at higher percentages. The peptide portion sits in the low-irritation, rapid-degradation regime. No CIR or SCCS opinion exists for this conjugate. Independent peer-reviewed efficacy data is essentially absent.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Niacin-mediated effects
  • Low irritation at typical levels

Known concerns

  • Possible transient flushing in sensitive users
  • Limited independent data
  • No regulatory dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.