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Skin Conditioning

OCTACARBOXYMETHYL DIPEPTIDE-12 LYSINAMIDE

CAS -
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A dipeptide-12 lysinamide with eight carboxymethyl groups — highly water-soluble skin-conditioning peptide. Evidence is entirely supplier-level.

Octacarboxymethyl dipeptide-12 lysinamide is an aggressively carboxymethylated derivative of a dipeptide amidated with lysine. Eight carboxymethyl groups make the molecule highly water-soluble and give it metal-chelating character on top of standard peptide-signal claims. No CIR or SCCS monograph covers this specific grade, and public efficacy data is limited to supplier brochures. As with other short modified peptides, class-level safety is reassuring and use levels are typically in the ppm range, but there is not enough independent evidence to move it above mid-yellow.

Function

HUMECTANT

Skin benefits

  • Skin-conditioning signal
  • Water-soluble with mild chelation
  • Low use levels

Known concerns

  • No independent safety or efficacy review
  • Proprietary structure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.