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Skin Conditioning

OCTAPEPTIDE-64

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic 8-amino-acid peptide supplied for skin conditioning. Plausibly safe at the trace levels used, but data is limited.

Octapeptide-64 is a synthetic 8-residue peptide marketed as a cosmetic skin-conditioning active, typically used at parts-per-million levels. Numbered INCI octapeptides of this kind are produced by specialty ingredient suppliers and sold for signaling-type benefits such as visible-aging support. There is no CIR or SCCS monograph for this peptide and no public GHS classification. As with other short peptides, intact skin penetration is negligible and irritation potential at use levels is very low. The main caveat is that independent efficacy and long-term safety data are sparse; risk in real formulations is dominated by carrier, preservative, and counterion choices.

Function

SKIN PROTECTING, SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Skin conditioning
  • Marketed signaling support
  • Low irritation potential

Known concerns

  • No regulatory monograph
  • Sparse independent data
  • Supplier-driven efficacy claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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Check your shelf

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.