Skin Conditioning
OLIGOPEPTIDE-127 RH-OLIGOPEPTIDE-1
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A 65-amino-acid fusion peptide produced in E. coli, pairing Oligopeptide-127 with a recombinant human EGF-like sequence. EU Annex III lists the rh-Oligopeptide-1 component, so concentration limits apply.
Function
Skin benefits
- Skin conditioning via growth factor activity
- Recombinant production for purity
- Combines two functional peptide sequences
Known concerns
- EU Annex III/416 restriction on rh-Oligopeptide-1 component
- Growth factor activity raises long-term skin signalling questions
- Stability and immunogenicity considerations
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.