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Skin Conditioning

OLIGOPEPTIDE-127 RH-OLIGOPEPTIDE-1

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A 65-amino-acid fusion peptide produced in E. coli, pairing Oligopeptide-127 with a recombinant human EGF-like sequence. EU Annex III lists the rh-Oligopeptide-1 component, so concentration limits apply.

Function

SKIN CONDITIONING - EMOLLIENTSKIN CONDITIONING

Skin benefits

  • Skin conditioning via growth factor activity
  • Recombinant production for purity
  • Combines two functional peptide sequences

Known concerns

  • EU Annex III/416 restriction on rh-Oligopeptide-1 component
  • Growth factor activity raises long-term skin signalling questions
  • Stability and immunogenicity considerations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Same plant / compound family

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.