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oxilofrine

CAS 365-26-4
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Oxilofrine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Oxilofrine (4-hydroxyamphetamine) is a synthetic cathinone derivative and beta-adrenergic stimulant. Its structural relationship to amphetamine and ephedrine places it in the restricted sympathomimetic amine category under EU cosmetics regulation. The compound shows cardiovascular stimulant activity and has been associated with adverse cardiac events in clinical use, precluding its inclusion in cosmetic formulations. It is not listed in CosIng with approved cosmetic functions.

Known concerns

  • Sympathomimetic stimulant with cardiovascular risk
  • Structural relation to restricted amphetamine derivatives
  • No EU cosmetics approval
  • Beta-adrenergic activity concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.