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P-CYMENE

CAS 99-87-6
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

P-Cymene is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

p-Cymene (4-isopropyltoluene) is an aromatic hydrocarbon that occurs naturally in over 100 essential oils including cumin, thyme, and coriander. It functions primarily as a fragrance ingredient and is not subject to significant restriction under EU Regulation 1223/2009. However, like other terpene hydrocarbons, p-cymene is prone to auto-oxidation, forming peroxides and hydroperoxides that can act as skin sensitizers. The SCCS recommends antioxidant stabilization (e.g., with BHT or alpha-tocopherol) for products containing terpenes to prevent oxidation before consumer use. The EU requires allergen labeling for natural fragrance components derived from essential oils containing p-cymene when above threshold concentrations.

Skin benefits

  • Natural aromatic component in essential oils
  • Widely found in food and cosmetic grade natural extracts

Known concerns

  • Auto-oxidation to skin-sensitizing peroxide products
  • EU allergen labeling for essential oil-derived p-cymene
  • Requires antioxidant protection for stable formulations
  • Concentration-dependent sensitization risk from oxidation products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.