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p-Phenetidine (4-Ethoxyaniline)

CAS 156-43-4
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

P-Phenetidine (4-Ethoxyaniline) is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

p-Phenetidine (4-ethoxyaniline) carries a 'Danger' signal word with extensive hazard warnings covering acute toxicity (H302/H312/H332), skin sensitization (H317), eye irritation (H319), reproductive toxicity (H361), organ toxicity (H372/H373), and aquatic toxicity (H401/H411). Its ethoxy-substituted aromatic amine structure makes it unsuitable for cosmetic use in any EU market.

Known concerns

  • EU Annex II prohibited cosmetic ingredient
  • Reproductive toxicity (H361 - Danger signal word)
  • Target organ toxicity repeated exposure (H372/H373)
  • Skin sensitizer (H317)
  • Acute oral/dermal/inhalation toxicity
  • Aquatic toxicity (H401/H411)
  • Suspected mutagenicity (H341)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.