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Hair Dye

P-PHENYLENEDIAMINE HYDROXYETHYL ETHER

CAS 126335-43-1
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A para-phenylenediamine derivative used as an oxidative hair-dye precursor. Like the PPD family, it is a known strong skin sensitiser and is heavily restricted under EU Annex III — not for general skincare.

Function

HAIR DYEING

Skin benefits

  • Used as an oxidative hair-dye intermediate

Known concerns

  • EU CLP / SCCS: classified as a strong skin sensitiser
  • Documented allergic contact dermatitis from PPD-class dyes
  • Highly restricted under EU Annex III
  • Cross-reactivity with other PPD-class compounds
  • Not for skin or facial leave-on use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.