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Hair Dye

2-NITRO-P-PHENYLENEDIAMINE DIHYDROCHLORIDE

CAS 18266-52-9 Updated
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A nitro-phenylenediamine hair-dye intermediate. Not permitted in EU hair dyes; documented sensitizer with mutagenicity flags.

Function

HAIR DYEING

Skin benefits

  • Historical use as red-violet hair dye

Known concerns

  • Banned for hair-dye use in the EU (Annex II / III restrictions)
  • Potential human skin sensitizer
  • Mutagenic in some bacterial assays
  • Hepatocellular tumors in female mice at high doses

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.