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2-NITRO-P-PHENYLENEDIAMINE SULFATE

CAS 68239-83-8
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A nitro aromatic hair dye intermediate restricted in the EU (Annex III/II/1319) and carrying skin sensitization warnings.

2-Nitro-p-phenylenediamine sulfate is an oxidative hair dye intermediate classified under EU Annex III (list of substances which cosmetic products must not contain except subject to the restrictions laid down), specifically reference II/1319. It carries GHS hazard H317 (may cause allergic skin reaction). The SCCS has assessed nitro-aromatic hair dye intermediates and recommended strict concentration limits, with this substance among those subject to in vivo sensitization confirmation requirements.

Skin benefits

  • Produces warm red-orange tones in oxidative hair dyeing
  • Used as a primary intermediate in combination with couplers

Known concerns

  • Skin sensitization (H317) - may cause allergic skin reactions
  • EU Annex III restricted substance (II/1319)
  • SCCS requires strict concentration limits for nitro aromatic hair dyes
  • Potential cross-reactivity with other azo dye intermediates

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.