Other
2-Nitro-N1-phenyl-benzene-1,4- diamine
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
2-nitro-n1-phenyl-benzene-1,4- Diamine is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
2-Nitro-N1-phenyl-benzene-1,4-diamine (also called 4-amino-2-nitro-N-phenylaniline) is an aromatic diamine used as a coupling agent in oxidative hair dye formulations. It carries GHS warnings for acute toxicity (H302), skin sensitization (H317), and serious eye irritation (H319). The EU Annex III listing restricts its maximum concentration to 1.0% in the final cosmetic product and requires oxidative conditions for safe use. Hair dye intermediates in this nitro-aromatic class are known for higher sensitization potential compared to other diamine couplers, driving the EU concentration restriction.
Known concerns
- GHS H302: harmful if swallowed
- GHS H317: may cause skin sensitization
- GHS H319: causes serious eye irritation
- EU Annex III restricted to max 1.0% concentration in hair dye formulations
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.