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3-Methyl-1-phenyl-5-pyrazolone

CAS 89-25-8
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

3-methyl-1-phenyl-5-pyrazolone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

3-Methyl-1-phenyl-5-pyrazolone (also called edarubicin or suceptibly related to antipyrine) is a phenyl-substituted five-membered heterocycle used in dye synthesis and pharmaceutical applications. It carries multiple GHS hazard classifications including acute oral toxicity (H302), skin and respiratory irritation (H315, H319, H335), and aquatic toxicity (H412). While not specifically restricted in EU cosmetics regulation, the multiple hazard classifications and heterocyclic structure warrant caution in any cosmetic application.

Known concerns

  • Harmful if swallowed (H302)
  • Causes skin irritation (H315)
  • May cause an allergic skin reaction (H317)
  • Causes serious eye irritation (H319)
  • May cause respiratory irritation (H335)
  • Harmful to aquatic life with long-lasting effects (H412)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.