Peptide / signal peptide complex
PALMITOYL SH-PENTAPEPTIDE-17 SP LYSINE AMIDOPROPYL DIGLYCOLPROPYLAMINE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A palmitoylated synthetic peptide paired with a lysine-based carrier amine, marketed as an anti-aging signal peptide intended to support collagen and skin firmness at low use levels.
Function
Skin benefits
- Lipidated signal peptide designed to penetrate stratum corneum and reach fibroblasts
- Class precedent for stimulating collagen and ECM-protein synthesis via signaling pathways
- Used at very low concentrations (typically <1%), limiting systemic exposure
- Lysine amidopropyl carrier moiety improves delivery and stability in formulation
Known concerns
- Multi-component proprietary peptide complex with limited public toxicology dossier
- No dedicated CIR or SCCS opinion located for this exact INCI variant
- Synthetic peptide-carrier conjugates can carry residual coupling reagents from manufacture
- Efficacy claims rely on in vitro and supplier data rather than peer-reviewed clinical evidence
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Same plant / compound family
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.