Skin Conditioning
PALMITOYL SH-PENTAPEPTIDE-4
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A palmitic-acid-anchored signal peptide (Matrixyl-class) that prompts skin to synthesise more collagen. Used at trace levels with one of the strongest safety records among cosmetic peptides.
Function
Skin benefits
- Stimulates collagen and ECM synthesis
- Well-studied anti-wrinkle peptide
- Very low irritation
- Effective at parts-per-million levels
Known concerns
- Marketing claims often exceed evidence
- Possible synthesis residuals
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.