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Skin Conditioning

PALMITOYL SH-PENTAPEPTIDE-4 SP AMIDE

Updated
88

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A palmitoyl pentapeptide (Matrixyl-class) — one of the most studied collagen-boosting cosmetic peptides. Used at trace levels with a strong safety record and meaningful published efficacy data.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Promotes collagen and ECM synthesis (well-documented for parent peptide)
  • Among the most clinically supported cosmetic peptides
  • Low irritation at typical use levels (1-5 ppm)

Known concerns

  • Real-world efficacy depends heavily on formulation and concentration
  • Photoinstability — needs proper packaging

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.