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PEG-500

CAS 25322-68-3
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A high-molecular-weight polyethylene glycol used as a viscosity-controlling agent and humectant that helps products maintain their texture and retain moisture over time.

PEG-500 is a polymer of ethylene oxide with an average of 500 repeating units, giving it a high molecular weight. EU Cosmetics Regulation permits PEGs of this type without specific concentration limits; however, manufacturers must ensure the final product is free from harmful levels of residual monomers. High EO polymers are generally well-tolerated and show minimal skin penetration due to their large molecular size.

Skin benefits

  • Humectant properties help retain moisture in skin formulations
  • Viscosity-controlling agent improves product texture and stability

Known concerns

  • Residual ethylene oxide and 1,4-dioxane must be monitored and kept below regulatory thresholds
  • High molecular weight reduces but does not eliminate skin absorption concerns in damaged barrier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.