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Skin Conditioning

PETASITES JAPONICUS GIGANTEUS LEAF EXTRACT

Updated
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Giant butterbur leaf extract — a Petasites botanical that naturally contains hepatotoxic pyrrolizidine alkaloids. EU restricts PAs because of liver toxicity and carcinogenicity; only PA-free grades should be considered.

Function

HUMECTANT

Skin benefits

  • Traditional medicinal use
  • Sesquiterpene content

Known concerns

  • Contains hepatotoxic pyrrolizidine alkaloids
  • PA carcinogenicity (IARC class concern)
  • EU strict PA limits
  • Liver toxicity
  • Default-down for genotoxic constituent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.