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PHENYLACETALDEHYDE GLYCERYL 1,3-CYCLIC ACETAL

CAS 4740-79-8
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A fragrance ingredient formed by condensation of phenylacetaldehyde with glycerin, used as a fixative and scent modifier in perfume compositions. Evaluated by IFRA with no major safety concerns at current use levels.

This cyclic acetal is formed by the reaction of phenylacetaldehyde with glycerin under acid catalysis, producing a fragrance material with fixative properties. It is not listed in EU Cosmetics Regulation Annex II (banned) or Annex III (restricted), indicating general safety at current exposure levels. The IFRA (International Fragrance Association) evaluation does not impose concentration limits for this material. No significant hazard statements are associated with its use in fragrance applications.

Known concerns

  • May contribute to overall fragrance allergen load in sensitized individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.